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1·Recently, drug therapy of advanced disease has been revolutionized by new agents.

近年来，新型药物的出现已经引起了进展期疾病药物治疗的变革。

2·More than 90% of patients diagnosed early can be cured, as can many with advanced disease.

早期诊断的病人90%以上都能治愈，即使晚期病人也有许多可以治愈。

3·KIT expression was associated with advanced disease and with decreased incidence of bone metastases.

KIT的表达情况与疾病晚期和减少骨转移的发病率有关。

4·It is already being done in early breast cancer, but we must do it also in advanced disease, she said.

“这就是规范化治疗，这在早期乳腺癌已经实现，但我们在晚期乳腺癌也必须这样做，”她说。

5·Fortekor increases the appetite, quality of life and survival time of the cats, particularly in advanced disease.

Fortekor增加食欲，特别是在先进的疾病生命和生存质量的猫时间。

6·Patients without significant fibrosis should wait. Those with more advanced disease should consider therapy today.

没有出现严重纤维化的肝炎病人应当等待，而症状比较严重的病人现在就应当考虑进行治疗。

7·When symptoms emerge, the patient is often already in an advanced disease stage where the central nervous system is affected.

出现症状时，患者常常已到疾病晚期，中枢神经系统受到影响。

8·The treatment, involving injections in a doctor's office, can help men with more advanced disease when used with surgery or radiation.

在医生办公室里进行注射的这项治疗对更晚期疾病时通过手术或放射治疗的男性能有所帮助。

9·The main risk factors were long time hospitalization, advanced disease, elderly leukopenia, chemotherapy and all kinds of invasive operations.

长期住院、晚期肿瘤患者、老年人、白细胞下降、化疗、各种介入性操作是医院感染的主要危险因素。

10·More recently, the emergence of neo-adjuvant chemoradiotherapy has fundamentally changed the management of patients with locally advanced disease.

最近，新辅助放化疗的出现已经根本改变了限局型浸润型结肠癌患者的治疗方式。