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1·He was despondent over the breakup of his marriage.

他为婚姻破裂而沮丧。《柯林斯英汉双解大词典》

2·She was becoming increasingly despondent about the way things were going.

她对情况的发展越来越失望。《牛津词典》

3·Joy and sadness are experienced by people in all cultures around the world, but how can we tell when other people are happy or despondent?

快乐和悲伤是世界上不同文化的人都会经历的，但我们怎样得知别人是快乐还是沮丧呢？

4·And for the despondent, some hope.

而对于失望者，给他们一些希望。

5·We head back to our caves, despondent.

我们只能失望地回到山洞里。

6·Don't be so despondent.

不要这样泄气。

7·You are despondent are on constellation.

你的抑郁是，地上的星座。

8·You are despondent are, on constellation.

你的抑郁是，地上的星座。

9·He leans back against the wall despondent.

他靠着墙，沮丧的。

10·To say I was despondent is an understatement.

说我有些沮丧已经算是轻描淡写了。