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1·Intraspinal commonly used drug methotrexate and cytarabine.

椎管内常用的药物有甲氨喋呤及阿糖胞苷。

2·The pretreatment regimen was Cytarabine, Etoposide, Cyclophosphamide and total body irradiation.

预处理选用阿糖胞苷、足叶乙苷、环磷酰胺和全身照射。

3·Drugs such as methotrexate, cytarabine and hydrocortisone are injected into the spinal fluid to prevent CNS leukemia.

甲氨蝶呤、阿糖胞苷和皮质醇等药物被注射到患者的脊髓液中，以预防中枢神经系统白血病的发生。

4·Methods Rats skin in vitro was applied, studying the effect of different concentrations of azone in Cytarabine ointment on drug permeation.

方法采用小鼠离体皮肤作为渗透屏障，研究不同浓度氮酮对阿糖胞苷促渗作用的影响。

5·AIM:To observe the pharmacokinetics and adverse drug reaction (ADR) after high dose cytarabine maintenanced chemotherapy in 5 children with acute nonlymphocytic leukemia (ANLL).

目的：了解大剂量阿糖胞苷化疗后，患者的药物动力学参数及不良反应。

阿糖胞苷

1·Intraspinal commonly used drug methotrexate and cytarabine.

椎管内常用的药物有甲氨喋呤及阿糖胞苷。

2·Methods Rats skin in vitro was applied, studying the effect of different concentrations of azone in Cytarabine ointment on drug permeation.

方法采用小鼠离体皮肤作为渗透屏障，研究不同浓度氮酮对阿糖胞苷促渗作用的影响。

3·Drugs such as methotrexate, cytarabine and hydrocortisone are injected into the spinal fluid to prevent CNS leukemia.

甲氨蝶呤、阿糖胞苷和皮质醇等药物被注射到患者的脊髓液中，以预防中枢神经系统白血病的发生。

4·AIM:To observe the pharmacokinetics and adverse drug reaction (ADR) after high dose cytarabine maintenanced chemotherapy in 5 children with acute nonlymphocytic leukemia (ANLL).

目的：了解大剂量阿糖胞苷化疗后，患者的药物动力学参数及不良反应。