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1·Objective To investigate whether genomic imprinting is involved in the etiology of tic disorder.

目的研究遗传印迹是否与抽动障碍的遗传病因学有关。

2·In particular, many principles of the epigenetic control of genome function have been uncovered by studies of genomic imprinting.

尤其是许多原则的表观遗传控制的基因功能的研究已发现了由基因组印记。

3·The methylation of histone H3-K27 was proved to be linked to several silencing phenomena including homeotic-gene silencing, X inactivation and genomic imprinting.

组蛋白H3第27位赖氨酸的甲基化与同源盒基因沉默、X染色体失活、基因印记等基因沉默现象有关；

4·Conclusion Parental specific expression exists in the transmission of tic disorder, which gives evidence that genomic imprinting may be involved in the genetic mechanism of tic disorder.

结论抽动障碍的传递存在亲源特异性表达，抽动障碍病因学中可能存在遗传印迹机制。

5·Because we have identical DNA in each of our cells, our bodies have mechanisms, such as DNA methylation, to control which genes are expressed in certain cell types-a process called genomic imprinting.

因为我们每个细胞含有完全相同的DNA，我们机体有许多机制，如DNA甲基化，来控制一定类型细胞的基因表达，该过程称为基因组印迹。