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1·You are making a big mistake.

你正在犯一个严重的错误。《牛津词典》

2·It was a big mistake on my part to have trusted her.

我相信了她，这是我的一大错误。《牛津词典》

3·If we had a big mistake in the experiment, we needed to analyze why it happened and what we should do to avoid it next time.

如果我们在实验中犯了大的错误，我们需要分析为什么会出现这种情况，以及下次应该如何避免。

4·You are making a big mistake, Pinocchio.

你犯了个大错误，皮诺乔。

5·It is a big mistake to try not to make mistakes.

试着不犯错是一个大错误。

6·In April of that year, Gerald Ratner made a big mistake.

在那一年4月，杰拉尔德·拉特纳犯了一个大错误。

7·He made a big mistake. I don't know what will happen next.

他犯了个大错误，我不知道接下来会发生些什么。

8·Soon after the match resumed, his rival made a big mistake.

比赛继续开始后，他的对手犯了一个大错误。

9·But in April of that year, Gerald Ratner made a big mistake.

但那一年的4月，杰拉尔德·拉特纳犯了一个大错误。

10·He made one big mistake, and, as a result, lost his job.

他犯了个大错，结果丢了工作。《牛津词典》