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1·Methods EAE were induced in guinea pigs.

方法应用豚鼠诱导EAE动物模型。

2·Objective:To study the curative effect of EAE with DT390-IL2 recombinant plasmid.

目的：研究DT390-IL2重组质粒对实验性变态反应性脑脊髓炎（EAE）的治疗效果。

3·Objective: To induce the EAE model on Guinea pig wi th Myelin Basic Protein (MBP).

目的：用髓鞘碱性蛋白(MBP)诱导实验性变态反应性脑脊髓炎(eae)豚鼠模型。

4·Methods The female guinea pigs were divided randomly into control group, EAE group and i. p. MBP group.

方法将雌性豚鼠随机分为对照组、EAE组和腹腔注射MBP组。

5·The application of 1, 25-dihydroxyvitamin D3 can treat and prevent EAE and made the its symptom relieve.

应用1，25二羟基维生素D3治疗和预防实验性变态反应性脑脊髓炎，可使其症状缓解。

6·During EAE BBB destruction involved many factors and up-regulation expression of ICAM-1 may play an important role.

EAE时BBB破坏的参与因素很多，ICAM一1的上调表达在其中起了重要的作用。

7·Magnetic transfer imaging, together with USPIO enhancement scan, was helpful to determine the features of the EAE lesions.

与uspio增强扫描相结合，磁化传递成像能够提示EAE病变的性质。

8·EAE can be induced actived by syngeneic or heterogeneous antigen from white matter of CNS. It shares many feathers with MS.

EAE可以用同种或异种中枢神经系统白质抗原主动诱导敏感动物发病，与MS有很多共同的特点。

9·Objective To construct animal model for further elucidating the pathogenesis of experimental allergic encephalomyelitis (EAE).

目的建立实验性变应性脑脊髓炎(eae)动物模型，为进一步研究其发病机制提供依据。

10·Conclusions Blood brain barrier damage during the earlier period of EAE might play an important role in the pathogenesis of EAE.

结论血-脑脊液屏障的早期损害在EAE发病过程中具关键作用。