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1·Conclusion Bufalin is effective to inhibit the growth of mice S180 sarcoma.

结论蟾蜍灵对小鼠s180肉瘤有抑制作用。

2·Conclusion: ERK negatively regulated the apoptosis induced by bufalin in K562 cells.

结论：ERK负向调节蟾蜍灵诱导的K562细胞凋亡过程。

3·Result Bufalin had inhibition growth effect on ECV304 cells with different level, and had concentration and time dependence.

结果蟾毒灵对ECV304细胞的生长有抑制作用，且呈浓度和时间的依赖性。

4·Objective: To explore the effect of extracellular signal-regulated kinase(ERK) on the apoptosis induced by bufalin in K562 cells.

目的：探讨细胞外信号调解激酶（ERK）对蟾蜍灵诱导白血病细胞凋亡的影响。

5·Conclusion the combination of ATRA with bufalin can significantly enhance the differentiation of NB4 cells in vitro culture by ATRA.

结论：蟾蜍灵抑制nb 4细胞活力及诱导细胞发生凋亡，蟾蜍灵与atra联合应用可显著增强A TRA对NB 4细胞的诱导分化作用。