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1·The biology and function of exosomes in cancer.

外泌体在癌症中的生物功能。

2·Indeed, donor cells can re-uptake their secreted exosomes.

事实上，供体细胞可再吸收它们自身分泌的外泌体。

3·However, TYRP2 concentrations in exosomes did not differ between these three groups.

然而，三组人群血清胞外体中TYRP2的浓度没有无差异。

4·It is intriguing how the recipient cells uptake exosomes and how recipient cells are chosen.

受体细胞是如何摄取外泌体的并且受体细胞是如何被选择的是件有趣的事情。

5·The main challenges of using exosomes in cancer diagnosis are 1) sensitivity and specificity.

使用外泌体诊断癌症的主要挑战是：1）灵敏度和特异性。

6·However, currently only a few clinical trials using exosomes in cancer therapy are implemented.

然而，在癌症治疗的应用上，外泌体目前仅有少数临床试验实施。

7·Future studies should clarify the complex mechanism of exosomes for more efficacious clinical trials.

未来的研究应该明确外泌体的复杂机制以更有效地用于临床试验。

8·A considerable amount of exosomes was detected in PD mouse brain following intranasal administration.

在鼻腔给药后在小鼠的大脑中检测到了大量的外泌体。

9·Therefore, exosomes emerge as favorable candidate carriers for therapeutics of cancer and other diseases.

因此，外泌体是一种很好的可用于癌症和其他疾病的治疗候选载体。

10·Dendritic cell-derived exosomes can induce anti-tumor immunity and have been used in clinical trials [3-5].

树突状细胞来源的外泌体可诱导抗肿瘤免疫并且已被应用于临床试验鹪[3 - 5]。