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1·The new drug has great significance for the treatment of the disease.

这种新药对于这种病的治疗有重大的意义。《牛津词典》

2·Since education is of great significance, the plan of reforming the current education system has been under discussion for a year.

因为教育意义重大，改革现行教育体制的计划已经讨论了一年。

3·Parents' love and caring are of great significance for children.

父母的爱和关怀对孩子是非常重要的。

4·I attach great significance to the news.

我认为这消息具有重大意义。

5·It is a matter of great significance.

这是一个非常重要的问题。

6·This is a matter of great significance.

这是一个具有重大意义的问题。

7·This is a time of great significance for Africa.

此时此刻对非洲具有重要意义。

8·Thought has great significance in the history of sports.

思想在历史运动中有巨大的意义。

9·Heart of appreciation is of great significance in our lives.

一颗懂得感恩之心是非常重要的。

10·The year 2011 also bears great significance on China-EU relations.

展望2011年，中欧关系将迎来具有重要意义的一年。