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1·He spoke slowly and with great difficulty.

他话说得很慢，而且很吃力。《牛津词典》

2·I had great difficulty getting off to sleep.

我很难入睡。《牛津词典》

3·With great difficulty, the fisherman manoeuvred his small craft close to the reef.

渔夫艰难地驾着小船靠近了礁石。《柯林斯英汉双解大词典》

4·He had great difficulty in speaking.

他说话有很大困难。

5·Zech Hipp was doing it with great difficulty.

泽赫·希普费了很大的劲才做到。

6·She dressed in haste, though with great difficulty, being nervous and excited.

尽管费了很大的劲，她还是匆匆忙忙地穿好衣服，显得既紧张又兴奋。

7·Americans have great difficulty understanding foreigners who always want to be with another person who dislikes being alone.

美国人很难理解外国人总是想和另一个不喜欢独处的人在一起的想法。

8·While a few countries are making major strides in this regard, the majority are having great difficulty even stemming the rate of increase, let alone reversing it.

虽然一些国家在这方面取得了显著的成果，但大多数国家就连降低（碳排放的）增长率都很难，更别说减排了。

9·American politicians have great difficulty recognizing that admitting more foreign students can greatly promote the national interest by increasing international understanding.

美国政界人士很难意识到，通过增进国际了解，招收更多的外国学生可以对国家极为有利。

10·This problem is one of great difficulty.

这个问题是一个大难题。