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1·Conclusion Losartan can down-regulate the expression of AT1R.

结论氯沙坦能下调AT1R的表达。

2·Furthermore, losartan can alleviate severe proteinuria induced by rapamycin.

氯沙坦可以减轻雷帕霉素所致的大量蛋白尿。

3·Losartan can reduce kidney lesions in adriamycin-induced nephropathy in rats.

推测氯沙坦能减轻阿霉素肾病大鼠的肾脏损害。

4·Objective: To evaluate the effect of losartan on left ventricular hypertrophy reversal.

目的：评价氯沙坦对高血压左心室肥厚的逆转作用。

5·Objective To observe the effect of losartan on hypertension and the heart rate variability.

目的观察氯沙坦的降压作用及其对心率变异性的影响。

6·Conclusion the mechanism of losartan in preventing atherosclerosis has little to do with lipid.

结论：氯沙坦抗动脉粥样硬化机制与血脂无关。

7·Method: 39 patients were treated with losartan and 35 were treated with captopril for 6 months.

方法：分别对39名高血压病人用科素亚及35名高血压病人用卡托普利治疗6个月。

8·Objective To investigate the clinical effect of Losartan on patients with chronic glomerulonephritis.

目的探讨科素亚治疗慢性肾小球肾炎的临床疗效。

9·Objective To evaluate the renal protective effects of losartan in treatment of chronic renal impairment.

目的评价氯沙坦在治疗慢性肾功能不全伴高血压时对肾脏的保护作用。

10·Chronic cough occurred in 12 patients receiving enalapril, 6 receiving losartan, and 4 receiving placebo.

慢性咳嗽在依那普利组有12例、在氯沙坦组有6例而安慰剂组有4例。

氯沙坦

1·ObjectiveTo observe the effects of combination of losartan and plendil for patients with chronic renal failure complicated hypertension.

目的观察氯沙坦与波依定联合用药治疗慢性肾衰竭并高血压的效果。

2·Objective To compare the long term safety and efficacy of fosinopril and losartan in the treatment of ischemic heart failure with chronic obstructive pulmonary disease(COPD).

目的比较福辛普利与氯沙坦治疗冠心病心衰伴慢性阻塞性肺部疾病的长期疗效和安全性。

3·Objective To investigate the efficacy and antiproteinuric effect of losartan in the treatment of mild to moderate essential hypertension.

目的探讨氯沙坦治疗轻、中度原发性高血压的疗效和对尿清蛋白的影响。

4·Objective To evaluate the renal protective effects of losartan in treatment of chronic renal impairment.

目的评价氯沙坦在治疗慢性肾功能不全伴高血压时对肾脏的保护作用。

5·AIM: to compare the clinical efficacy of fosinopril and losartan in the treatment of heart failure and its influence to the renin angiotensin system.

目的：比较福辛普利和氯沙坦治疗心力衰竭的疗效及对肾素血管紧张肽系统的影响。

洛沙坦

1·Objective: To investigate the structural changes of aorta in spontaneously hypertensive rats (SHR), and the protective role of enalapril and losartan.

目的：观察自发性高血压大鼠胸主动脉结构的改变，以及依那普利和洛沙坦的保护作用。