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1·Methods tropisetron hydrochloride was synthesized from indol-3-yl carboxylic acid by chlorination and condensation with tropic alcohol lithium, then salt formation with hydrochlororic acid.

方法：以吲哚-3-甲酸为起始原料，酰氯化后与托品醇锂发生缩合反应，再与盐酸成盐制得盐酸托烷司琼。

2·Tropisetron Hydrochloride was synthesized from 1Hindol-3-carboxylic acid by chloride acetylation and condensation with Tropic alcohol.

以3-吲哚甲酸为起始原料，经氯化亚砜酰氯化、与托品醇缩合合成了托烷司琼盐酸盐。