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1·They're bunch of bigheaded, inbreds with breathing problems.

他们是一群自大鬼，先天就有呼吸问题。

2·The constant flattery from his subordinates made him bigheaded.

不断被下属赞美，他变得非常自大。

3·This coyness may be no crime, but a genuine wish not to appear bigheaded for their association with an institution that is shorthand for the acme of academe.

这种矫情不是什么罪，可能只是真心希望不要因为自己归属于一个堪称学术巅峰代名词的机构而显得自大。